Our team understands the crucial role of rigorous neurological assessments, biomarkers, neuroimaging techniques, and the use of appropriate clinical endpoints in neuroscience trials.

We offer extensive experience across a range of neurological conditions, including:
  • Dementia, Alzheimer's and Parkinson’s
  • Epileptiform disorders
  • Other neurodegenerative diseases
  • Movement disorders
  • Rare genetic neurological conditions

Pain points associated with clinical trials in neuroscience

  • Patient Recruitment and Retention: Neurological disorders can be rare and recruiting enough eligible participants for a study can be challenging. Moreover, due to the chronic or progressive nature of many conditions, retaining participants for the duration of the trial can be tough.
  • Complexity of Endpoints: Neurological outcomes can be subjective and may require specialized scales or biomarkers. Ensuring consistency and reliability in endpoint measurements across different investigators and sites can be challenging.
  • Safety Monitoring: Some neurological interventions, especially those that are invasive or novel, may carry significant risks. Monitoring for adverse events and ensuring participant safety is paramount.
  • Heterogeneity of Diseases: Neurological disorders can manifest in various ways in different patients, making it difficult to group patients and interpret results.
  • Long Study Duration: Many neurological disorders progress slowly, requiring long study durations to observe therapeutic effects or disease progression, which can be resource-intensive.

How iNGENū addresses these pain points

  • Enhanced Recruitment Strategies: iNGENū leverages a global network of research sites and patient advocacy groups, utilizing advanced data analytics to target and recruit suitable participants efficiently. Through continuous patient engagement and education, we ensure high retention rates throughout our trials.
  • Standardization and Training: We implement standardized protocols for all endpoint assessments and provide intensive training for investigators and site personnel. By employing advanced digital tools, we ensure data consistency and reduce variability across sites.
  • Rigorous Safety Protocols: We have established robust safety monitoring systems, with real-time data tracking and quick response mechanisms, ensuring the well-being of participants is prioritized at every stage.
  • Personalized Approach: Recognizing the diverse nature of neurological diseases, we employ stratification techniques and personalized medicine approaches. This helps in grouping patients more effectively and interpreting data in a more nuanced manner.
  • Innovative Trial Designs: To counteract the long durations often required in neurological trials, we adopt adaptive trial designs, interim analyses, and predictive modeling. This not only accelerates the trial process but also optimizes the use of resources.
Ready to discuss your trial?